AF Duration Linked to Outcomes After Stroke Thrombolysis

Eleanor McDermid, MedWire News

Patients with atrial fibrillation (AF) are at high risk for poor outcomes after receipt of recombinant tissue plasminogen activator (rtPA) for acute stroke, particularly if they have had the arrhythmia for a long time, research suggests.

"This information is useful to identify stroke patients at higher risk for adverse stroke outcomes following rtPA treatment who may benefit from closer blood pressure control and monitoring and, perhaps, early endovascular treatment," says Raymond Seet (Mayo Clinic, Rochester, Minn.) and team.

Patients with a first-ever AF episode did not appear to be at increased risk for poor outcomes, although the researchers note that they could not distinguish between patients with a genuine first episode and those who may have had undiagnosed paroxysmal AF.

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