Stroke Risk Declines After Cessation of HRT
The increased risk for stroke among women taking hormone replacement therapy (HRT) dissipates soon after stopping treatment, shows follow-up of the Women's Health Initiative (WHI).
The WHI Estrogen-Alone Trial randomly assigned 10,739 postmenopausal women with prior hysterectomy to receive conjugated equine estrogens (CEE) or placebo. The trial was halted a year early, after an average of 7.1 years, because of a significantly increased risk for stroke and deep vein thrombosis (DVT) among estrogen users.
The present study, which appears in JAMA, followed-up the women for an average of 10.7 years after treatment initiation (about 4 years after HRT cessation).
National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.